How to Cope with Organic Condensation Reactions – Part 1

A condensation reaction is a type of chemical reaction in which two molecules are combined to form a single molecule, usually with the loss of a small molecule, viz., Water (dehydration synthesis), Ammonia, alcohol, Acetic acid or Hydrogen sulfide.


Carbonyl compounds are popular as substrates for condensation reactions. The presence of an a-hydrogen is a required condition. These reactions are often base-catalyzed.

Question:

Predict the major product(s) of the following reactions:



Click/tap to enlarge the image

Solution infographic:



Click/tap to enlarge the image

Creepy condensations❓ Let Chemaficionado know in the comments below or at mychemistryhomework@gmail.com❗

References:

(1)    Bailey, S.; Davies, S. G.; Smith, A. D.; Withey, J. M. Asymmetric Synthesis of (1R,2S,3R)-γ-Methyl-Cis-Pentacin by a Kinetic Resolution Protocol. Chem. Commun. 2002, No. 23, 2910–2911. https://doi.org/10.1039/b209728c.

(2)    Condensation reaction. Wikipedia. https://en.wikipedia.org/wiki/Condensation_reaction.

(3)    Graham, T. W.; Fryhle, C. B.; Snyder, S. A. Organic Chemistry.; Hoboken, Nj John Wiley Et Sons, Inc, 2016.

(4)    Brown, C.; Ford, M. Higher Level Chemistry, 2nd ed.; Pearson Education: Harlow, Essex, 2014.

(5)    Ncert. Chemistry : Textbook for Class XI - Part.II; National Council Of Educational Research And Training: New Delhi.

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