Wheel of Aryl-aryl Coupling
In an aryl-aryl cross-coupling reaction, two different aryl fragments are joined. Aryl-aryl cross-couplings, which are a subset of the more general coupling reactions, may involve carbon–carbon cross-coupling or carbon–heteroatom cross-coupling. Cross-coupling reactions frequently require metal catalysts. Wheel of aryl-aryl coupling: Click/tap to enlarge the image Name reactions on the infographic: Pschorr (intramolecular coupling) Graebe-Ullmann (intramolecular coupling) Ullmann (homo coupling) Gomberg-Bachmann Wittig (via benzyne mechanism) Kumada Negishi Stille Suzuki-Miyaura Hiyama Hiyama-Denmark Buchwald-Hartwig ( carbon–heteroatom cross-coupling ) Chan-Evans-Lam ( carbon–heteroatom cross-coupling ) Liebeskind-Srogl What other wheel(s) 🛞 of organic reactions would you like to see ❓ Let Chemaficionado know in the comments below or at mychemistryhomework@gmail.com ❗ References: (1) Roman A. Valiulin, ChemInfoGraphic . ChemInfoGraphic. https://chemi...