How to Deal with Carbonyl Compounds in Presence of a Base or a Nucleophile – Part 1

Carbonyl compounds are popular as substrates for condensation reactions. The presence of an α-hydrogen is a required condition. These reactions are often base-catalyzed.


What if an α-hydrogen is not present? What if the base is concentrated? What are the possibilities depending on the substrate?

Question:

Predict the major product(s) of the following reaction:



Click/tap to enlarge the image

Solution infographic:



Click/tap to enlarge the image

Ridiculous reagents❓ Let Chemaficionado know in the comments below or at mychemistryhomework@gmail.com❗

References:

(1)    Wikipedia Contributors. Cannizzaro reaction. Wikipedia.

‌(2)    Graham, T. W.; Fryhle, C. B.; Snyder, S. A. Organic Chemistry.; Hoboken, Nj John Wiley Et Sons, Inc, 2016.

(3)    Brown, C.; Ford, M. Higher Level Chemistry, 2nd ed.; Pearson Education: Harlow, Essex, 2014.

(4)    Ncert. Chemistry : Textbook for Class XII - Part.II; National Council Of Educational Research And Training: New Delhi.

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